Volume I: Causality and Attraction
Connects institutional conditions to protection of human life.
Media / Public health
The March 2020 Drug Reversal
A case study in how emergency policy reversed the practical meaning of accumulated exposure.
The video compares efficacy evidence with the separate axis of known human safety, asking what disappeared when a familiar medicine and a novel intervention were judged inside a rapidly changing authorization enclosure.
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Continue into the research
Related work
Volume VI: Nested Causal Models, Maps, and Interventions
Provides the method for separating observation, inference, and intervention.
A Volunteer to Exemplify the Problem
A companion essay on exposure, evidence, and consent.
Read the video transcript
Published captions, with their original wording.
In March 2020, the White House debated giving Americans access to two unproven COVID drugs, and Dr. Anthony Fauci's private diary reveals exactly why he intervened to stop it.
At the time, hydroxychloroquine and remdesivir shared one major similarity. Neither had any proven ability to fight the novel virus, but there was a massive difference in their basic human safety.
If you plot them, both score zero for COVID efficacy, but on the axis of accumulated human exposure, the gap is huge.
One had decades of known safety data. The other was completely experimental.
Fauci's diary shows he initially recognized this exact difference. He proposed flexible clinical access for the established drug, keeping the experimental one in strict trials.
But days later, decision makers completely collapsed these distinct categories. Human safety and disease efficacy were flattened into a single label, approved for COVID, forcing both drugs to drop to the exact same unapproved baseline.
As a result, officials shut down monitored, compassionate access to the established medicine entirely, just to protect randomized trials for the novel one.
This didn't just prioritize science over speculation. It created a category error, where an unproven indication retroactively erased a drug's entire history of human safety.